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[Wadden STEP 3, JAMA 2021] STEP 5 Trial (Nature Medicine 2022) Long-term data: patients maintained an average 15.2% weight loss over 2 years of continuous semaglutide use, with sustained metabolic improvements including reduced HbA1c, blood pressure, and waist circumference

doi: 10.1002/der2.70003

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s.c.) or vehicle, in a randomized order and, 3 hours later, were placed in the center of the open field and allowed free access for 15 minutes

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