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A lot of them have autoimmune disease and that inflammation too makes you feel bad
Every used needle goes directly into a sharps container
In SURMOUNT-5, gastrointestinal adverse events were the most common with both medications and were generally mild to moderate

For type 2 diabetes , NICE recommends GLP-1 receptor agonists as second- or third-line therapy when metformin and other oral agents have not achieved adequate glycaemic control, or as an alternative to insulin in certain circumstances

Br J Nutr 124:797808
