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Description
Protein Farnesyltransferase Inhibitor (Sch 66336) Abolishes Nf-Kappab Activation Induced By Various Carcinogens And Inflammatory Stimuli Leading To Suppression Of Nf-Kappab-Regulated Gene Expression And Up-Regulation Of Apoptosis
doi: 10.1038/nn.4399
GSH occurring in the sample reacts with 5,5-dithiobis(2-nitrobenzoic acid) (DTNB) to form the mixed disulfide GS-TNB and the chromophore 5-thio-2-nitrobenzoic acid (TNB)
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Since it does not involve the mechanism of leukocyte infiltration into the nervous system, its use minimizes the occurrence of progressive multifocal leukoencephalopathy (PML) [55]
