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These factors are potential therapeutic targets for diseases with both autophagy dysfunction and oxidative stress
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High levels of HO inactivate protective peptides like ACTH and -MSH, while decreasing enzyme activities like methionine sulfoxide reductase, consequently intensifying oxidative damage and accelerating melanocyte death 46

7 These dynamics resemble the complexities that young men who engage in informal work together in urban Ethiopia have to deal with as they balance affection and reciprocity (Mains 2013)

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Sawyer D.B., Colucci W.S
