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This work was supported in part by a KAKENHI grant from the Japan Society for the Promotion of Science [grant numbers 23K13883] (M.M.) and the Platform Project for Supporting Drug Discovery and Life Science Research (Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)) from AMED under Grant Number JP24ama121054 (M.A.)
From the analysis of the structure-activity relationship (SAR) studies, the pomalidomide-based PROTACs showed better results than the lenalidomide-based or VHL-based PROTACs

10.24272/j.issn.2095-8137.2024.062

In this reaction, GSH is lost from the cell and must be replaced
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