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In contrast, mice with hormone-induced hypercholesterolemia treated with the selective cholesterol uptake inhibitor ezetimibe showed significantly reduced tumor cell stemness and slower tumorigenesis, suggesting that cholesterol was critical for the increased malignancy of bladder cancer in these mice

Although there has been great progress in HD pathogenesis, currently available neuroprotective treatment strategies are still insufficient

Hindustan Lever Ltd., India)

This paper provides in vivo genetic and pharmacological evidence for the role of Gls in MYC-induced mouse liver cancer

doi: 10.1016/j.ejphar.2015.08.038 136 YunSPKamT-IPanickerNKimSOhYParkJ-Set al