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NHS laboratories generally define deficiency as a serum B12 below approximately 148 pmol/L (equivalent to roughly 200 ng/L or pg/mL), though reference ranges vary between laboratories and results should always be interpreted in the context of local ranges and the patient's clinical presentation

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Minor side effects such as brief soreness at the injection site are normal and resolve quickly

Without patent protection, no pharmaceutical company can recoup the $100M+ cost of running the clinical trials required for FDA approval