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Their white epididymal and brown interscapular adipose tissues were dissected, weighed, and frozen in liquid nitrogen for later RNA analysis

Genetic nicotinamide N-methyltransferase (Nnmt) deficiency in male mice improves insulin sensitivity in diet-induced obesity but does not affect glucose tolerance

However, no research directly compares continuous use versus cycling protocols (such as 12 weeks on, 4-8 weeks off), leaving optimal long-term strategies somewhat uncertain

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