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In cholangiocarcinoma, combined BET degradation and mTOR inhibition synergistically reduce acetylation of PSAT1-associated H3K27, inducing PSAT1 downregulation and subsequent dysfunction of the serine-glycine-one-carbon (SGOC) pathway (114)

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"Glutathione Depletion-Methylation Cycle Block: A Hypothesis For the Pathogenesis of Chronic Fatigue Syndrome"

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Injection sample volumes of 5 L were separated by an Xqua C8 column (2.1 mm 100 mm, 3.5 m, 100 ) at a flow rate of 0.25 mL/min with a gradient of 595% mobile phase B in 30 min

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Van Niel, G., DAngelo, G

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