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doi: 10.1016/j.chom.2017.01.005 310 KimM-SRohSWBaeJ-W

Protects the nervous system from pain and ailments

Reduced inflammation ( IL-6, TNF-) Lowered oxidative stress ( ROS, HO-1/NQO-1) Restored key barrier proteins (FLG, LOR, AQP3) Enhanced cell repair and anti-apoptotic activity This study unveils a new bio-based approach to photoprotection and barrier restoration, positioning fermented polysaccharides as promising ingredients for sensitive-skin and after-sun formulations

Nature 569 , 641648 (2019)

ROS-elicited Ca 2+ stimulates ERK, CREB, early genes
