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Regarding the SEV group, B12-upregulated genes had GO annotations related to cytoplasmic translation (tRNA and rRNA processing), adaptive immune response, ncRNA processing, miRNA-mediated gene silencing, proteasome-mediated ubiquitin-dependent protein catabolic process, cobalamin transport, and negative regulation of transcription by RNA polymerase II ( Figure S3 )

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More information can be found in the article: Vitamin B12 Deficiency and Anesthesia Conclusion: Vitamin B12 and Nerves In the research into vitamin B12, nerve health is one of the central topics

For some, the effects may be subtle at first or become noticeable only after repeat doses