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454 Strategic modulation of the gut mycobiota through dietary interventions, fecal microbiota transplantation, probiotic supplementation, and prebiotic administration has therapeutic potential in enhancing immunotherapy efficacy while mitigating immune-related adverse events

This can be achieved by reducing intracellular ROS production through low levels of mitochondrial respiration, elevated dependency on glycolytic phenotype, or enhanced capacity of antioxidant detoxification [58, 59]

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Liu L-H, Qiu W-X, Li B, et al