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Aoyagi, M
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J Neurosci 2005;25(3):662-71
Post-transcriptional regulation of GCLM also occurs with 4-HNE treatment, which increased the stability of GCLM mRNA by an unknown mechanism that required de novo protein synthesis [122]
In the future, there is a need to combine multi-omics technology to analyze the metabolic heterogeneity, develop multiple inhibitors targeting the compensatory pathway, and improve the killing effect of cancer cells through the combination of glutamine metabolism inhibition with immune checkpoint blockade, CAR-T therapy, and other applications
