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DISCUSSION This is the first study to demonstrate that ARA 290 appears to be safe when administered repeatedly over a 4-wk period to sarcoidosis patients with symptoms of SFN

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J Clin Endocrinol Metab (2020) 105:e45517

These anomalies were associated with significant increases in 4-hydroxynonenal (4-HNE), malondialdehyde (MDA), and iron in the midbrain of the A53T mice (Figure 1, DF)
