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At least for presynaptic terminals of cortico-striatal synapses, calcium influx from internal calcium stores was shown to prevent presynaptic BDNF release mediated via presynaptic NMDA receptors containing the GluN1 subunit (Park 2018) (Fig

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Consequently, as life expectancy increases and baby-boomers retire, the already heavy burden imposed by ESRD on the US health care system is predicted to increase dramatically
