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Higher doses are more effective for skin brightening because melanin inhibition is dose-dependent
Nevertheless, unlike findings from animal experiments, human studies did not show favorable results regarding liver function, fibrosis, or survival rates [37,38,39]

Effects of coenzyme Q10 administration on blood pressure and heart rate in adults: A systematic review and meta-analysis of randomized controlled trials
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Vitamin a supplementation for the prevention of bronchopulmonary dysplasia in preterm infants: an update