b12 injections change skin problems Hyperpigmentation as a Primary Symptom of Vitamin Deficiency: A Case Report Strange Rash/ Low B12 :

For best results, combine it with a low-glycemic diet, protein intake of at least 1.6g/kg , and moderate exercise (especially resistance and Zone-2 cardio)

Vitamin B12 injections allow for quicker absorption into the body and you feel the effects (increased energy, focus, improved sleep) within 48 - 72 hours and the effects last for about 1 week.

In these cases, additional tests such as methylmalonic acid or homocysteine may be requested to assess functional B12 status at the cellular level

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If you notice a lump of fatty tissue under your skin in the same place that you usually inject your medication, you may have lipohypertrophy