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RBC-coated NPs are among the first biomimetic formulations employed (Ding et al., 2016

(E) Flow cytometry results histogram of total ROS in hepatocytes

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The released Cu 2 O and degraded ZIF-67, respectively, generate Cu + and Co 2+ for CDT and O 2 , while the ZnPc consumes O 2 for PDT under laser irradiation, achieving synergistic PDT/CDT combination therapy