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Sandilands EA, Bateman DN

Isomerization of 9( R )-HpODE creates two hydroxy-epoxides possessing an epoxide at the 9(10)-position and a hydroxy at the 11- or 13-position, as well as the two corresponding ketones

Furthermore, GLY administration (1 g/kg for 21 d) was reported to attenuate the loss of fat and muscle mass and to reduce skeletal muscle inflammation in a mouse model of cancer cachexia (Reference Ham, Murphy and Chee25)

A 2017 review summarised neuroprotective properties of silymarin in animal models, including: Reduction of amyloidogenic activity (relevant in Alzheimer's research) Anti-inflammatory action in nerve tissue Reduction of oxidative stress in the brain Possible positive effects on cognitive function Possible reduction of stroke risk Whether these effects can be achieved in humans at attainable concentrations of silymarin in particular whether sufficient quantities can cross the blood-brain barrier remains unclear

Eat hormone free, grass-fed meats, grass-fed butter or ghee, and organic free-range eggs