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Furthermore, inflammation-driven BBB disruption appears to be a shared feature between AD and PD, with elevated cytokine and oxidative stress responses contributing to vascular damage in both diseases, although the specific molecular pathways involved remain better characterized in AD [98,100,110]
602 Epigallocatechin-3-gallate (EGCG), the primary polyphenol in green tea, inhibits iron inflow by inhibiting Malvolio expression, and promotes the upregulation of ferritin, which alleviates the increase of free iron levels in the brain of PD Drosophila
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doi: 10.1038/s41580-023-00648-1 35 JiangXPengQPengMOyangLWangHLiuQet al
Domnech, M., Hernndez, A., Plaja, A., Martnez-Balibrea, E
