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To identify pathways associated with the early response of KRAS G12V /MYC cells to combination treatment, gene set enrichment analysis (GSEA) using the KEGG database was performed

doi: 10.1111/imr.12833 58 KleinnijenhuisJQuintinJPreijersFJoostenLAIfrimDCSaeedSet al

The p53 protein, a critical tumor suppressor, is often altered or deactivated in various malignancies, making it an ideal target for therapeutic treatments

Although necroptosis is widely regarded as an immunogenic and therapeutically exploitable form of regulated cell death, accumulating evidence indicates that its biological consequences in multiple myeloma are not uniformly beneficial

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