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10.1248/bpb.b18-00712 [DOI] [PubMed] [Google Scholar] Lehwald N., Duhme C., Wildner M., Kuhn S., Frst G., Forbes S

Despite its known proapoptotic actions in the case of lymphoid malignancies [179], GCs were demonstrated to reduce the efficiency of various chemotherapeutic and radiotherapeutics regimens

Heres what the clinical data shows: Most Common: Nausea (affecting 15-44% of users), diarrhea (10-30%), vomiting (7-25%), and constipation (6-24%) Severity: 98.1% of gastrointestinal side effects are mild or moderate, with 99.5% being non-serious Duration: Median duration is 8 days for nausea, 3 days for diarrhea, and 2 days for vomiting Timing: Most side effects occur during initial weeks and dose escalation, declining over time Discontinuation: Only 4.3-10% of users discontinue therapy due to side effects Serious Events: Rare, with no increased risk of pancreatitis or malignancy in clinical trials Management: Slow dose titration, dietary modifications, and hydration significantly reduce symptoms Important Note: Weight loss is NOT caused by side effects

Supplementation may affect your existing illness or interact with drugs

Randomized clinical trial of brewed green and black tea in men with prostate cancer prior to prostatectomy