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In UC, iNOS is the primary key element responsible for increased NO synthesis in the epithelial cell and iNOS-derived NO promotes TNF--expansions in the intermediate and proximal intestine, which increases leukocyte infiltration primarily through activation of the formation of intracellular adhesion molecule (ICAM) and P-selectin, resulting in intestinal cellular injury (46)

Monitoring Intervals Beyond 3 Months Assuming the 3-month panel is reassuring, a maintenance monitoring schedule of every 3 to 6 months is reasonable for most adults in this age group

doi: 10.3390/nu13020438

Genetic screens may help identify previously uncharacterized genetic modifiers of susceptibility

This IV Drip contains Prescription Only Medicine that can only be administered by a GMC-registered doctor