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Astrocytes play a critical role in protecting the brain against oxidative stress

2013;305:G900G910

AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer
Cardiac sympathetic denervation, detectable via 123 I-MIBG scintigraphy, is strongly associated with disease progression ( Management complications: Cardiovascular symptoms complicate pharmacotherapy by interacting with anti-parkinsonian drugs that modulate autonomic tone, requiring dose balancing and often necessitating cardiology consultation ( 4.3 HIV co-infection and antiretroviral therapy HIV-positive individuals are at increased risk of parkinsonism due to basal ganglia vulnerability to viral neurotoxicity, chronic inflammation, and mitochondrial stress (Denaro et al., 2022

AD can be categorized into two main types: familial (accounting for 1-5% of AD cases) and sporadic forms (over 95% of cases)
