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Kidney Disease in Diabetic Patients: From Pathophysiology to Pharmacological Aspects with a Focus on Therapeutic Inertia

Purification and properties of pig heart crotonase and the presence of short chain and long chain enoyl coenzyme A hydratases in pig and guinea pig tissues

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Such processes promote hypertension through increased sympathetic activity and reninangiotensinaldosterone system (RAAS) activation, while dyslipidemia arises from altered hepatic lipid metabolism and increased very-low-density lipoprotein synthesis synthesis (13, 14)

Specifically, HTF significantly reduces triglyceride (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) levels in serum and liver, attenuates body weight gain and hepatic lipid accumulation, improves liver function indices [aspartate aminotransferase (AST) and lactate dehydrogenase], alleviates histopathological liver damage, and enhances systemic antioxidant capacity (48)