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Determination of steady state parameters for all the compounds was not possible due to low solubility at high micromolar concentrations

Additionally, it was confirmed that one of luteolin derivatives enhanced SOD1 mRNA and SOD activity and glutamate-cysteine ligase catalytic subunit (GCLc) mRNA and protein levels, whereas another one induced mRNA levels of GCLc only in mutant striatal cells

Mitochondrial quality control Cellular mechanisms that monitor, repair, remove or replace damaged mitochondrial components to maintain mitochondrial function