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Although the clinical implementation of LTF in AD is scarce, one pilot clinical trial of LTF in AD patients resulted in decreased inflammatory and oxidative stress markers with enhanced cognitive function in the LTF treated group after a 3-month period (Mohamed et al., 2019)
( Bmal1 (one of the essential clock genes that participate in the maintenance of the circadian periodicity at the cellular level) in mice suprachiasmatic nucleus (SCN) led to increased escape latencies and number of escape failures in the learned helplessness paradigm, induced higher immobility time in the tail suspension test, and decreased the time spent in the light compartment of the light/dark test
Pennisi et al
It is often used to treat facial wrinkles but has also been shown to have a significant benefit on stretch marks (referred to medically as striae)
However, these downsides often vary from person to person
