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15,276 The activation of GLP-1R is linked to decreased NF-B pathway activity Treatment with GLP-1RAs can effectively mitigate chondrocyte apoptosis caused by endoplasmic reticulum stress and alleviate the associated inflammatory response
doi:10.1038/nature09146 98. Port, R
Most patients notice the first changes within two weeks: Pain reduction and decreased inflammation come first, followed by improved range of motion and faster recovery as the protocol progresses
The peptide outperformed ranitidine, which produced only partial protection
