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10.1210/en.2011-1385 16 EdholmT.CejvanK.Abdel-HalimS

Internal state dynamics shape brainwide activity and foraging behaviour

This guide covers both, honestly, so you know what each category can and cannot do, who each is for, and where the money is well spent versus wasted

Their ability to suppress appetite, delay gastric emptying, and enhance insulin sensitivity positions them uniquely to combat the multifaceted drivers of obesity

Long-acting, subcutaneously administered, PYY RA are undergoing early phase clinical trials as obesity treatments either alone or in combination with GLP-1 RA (Table 1, NCT02568306 and NCT03574584)