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Historically, addressing weight and addiction have been treated as separate clinical problems a patient might see an endocrinologist for metabolic syndrome and an addiction specialist for alcohol dependence, with little coordination between them

At the same time, steep federal budget cuts to Medicaid shift financial pressure onto states, making it more likely that coverage will be reduced

Furthermore, these agonists may improve brain insulin sensitivity, reduce oxidative stress, and promote the survival of neurons

Those side effects led to more than 20 percent of participants in each dosage group dropping out during the course of the study