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While our current treatments have shown significant therapeutic benefits, there still appear to be some patients who, despite aggressive therapy, good adherence, and inhaler technique, continue to have exacerbations

In contrast, liraglutide alone sustains weight loss but does not significantly improve measured physical fitness outcomes.

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For those who want to go deeper: JAMA Psychiatry (2025):- GLP-1 RAs & Mental Health Meta-Analysis: JAMA Psychiatry (2025):- Semaglutide & Alcohol Use Disorder RCT: eClinicalMedicine / The Lancet (2024):- 12-Month Neurological & Psychiatric Outcomes of Semaglutide: APA Monitor (2025):- Mental Health Effects of GLP-1 Drugs (accessible overview):

There have been rumors swirling about whether Janelle Brown used Ozempic to achieve her recent weight loss