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3.3.2 Harms: Risk of Ketoacidosis: The major concern is the development of diabetic ketoacidosis (DKA), including euglycemic DKA
A small subset of patients (approximately 47% in clinical trials) discontinue semaglutide due to intolerable gastrointestinal side effects that do not adequately resolve

These are regulatory and operational standards that exist independently of patient reviews

SELECT: Semaglutides Rapid Cardiovascular Benefits (data from #ECO2025) In adults with obesity & established CVD (no diabetes), semaglutide 2.4 mg weekly: MACE by 41% within 6 months First significant benefit seen at day 20 53% in , 43% in nonfatal MI Early protectionbeyond weight loss

This helps maintain healthier blood sugar levels throughout the day
