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These sensory fibers innervate the gastrointestinal tract and project to the NTS, where GLP-1-producing neurons are also located [8]

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GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), and tirzepatide (Mounjaro) work by slowing gastric emptying and activating receptors in the brainstem, which can trigger nausea and vomiting

Biocytogens suite of humanized receptor mouse models offers a powerful translational platform to validate receptor-specific pharmacology and cross-species activity of these advanced molecules in a human-relevant context

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