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The drug would also likely be stopped in patients who continue to gain weight or in those who are not experiencing any weight loss on the drug
And this makes sense when considering the relationship between adipose accumulation and the resulting systemic disease contributing to HFpEF pathophysiology (Figure)
But researchers are increasingly seeing signs that some benefits may be weight-independent
GLP-1RAs are promising for treating obesity due to their effects on appetite and food intake
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