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After years of being told he was pre-diabetic, more detailed blood work revealed something earlier labs had missed: extremely high insulin levels

These effects, which are fundamental for the treatment of simple obesity, take on an even more potentially interesting importance when considered for the treatment of a disease such as lipedema, whose main characteristic seems to be the presence of inflamed, hypo-oxygenated and dysfunctional adipose tissue with fibrosis, extracellular matrix remodeling and lymphatic and vasculature dysfunction [1,35]

Impetus for this commentary is the report by Liu et al

It started with a little red wagon

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