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They were looking to see if GLP-1 use was linked to a reduced risk of serious mental health outcomesdefined in this study as hospitalization or extended work leave due to mental illness, or death by suicide

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For anxiety and depression that co-occur with diabetes and obesity, semaglutide and, to a lesser extent, liraglutide might be useful dually effective therapeutic options, the authors concluded

GLP-1 increased the ability of beta cells to antioxidize via extracellular regulated kinases pathway and nuclear factor erythroid 2-related factor 2 (Nrf2) translocation [129]