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Study population We implemented two active comparator, new user cohorts.26 The first cohort was composed of patients who started and continued on either a GLP-1 receptor agonist (dulaglutide, exenatide, liraglutide (except the 3 mg/0.5 mL formulation indicated for weight loss), lixisenatide, semaglutide) or a DPP-4 inhibitor (alogliptin, linagliptin, saxagliptin, sitagliptin, vildagliptin) for the first time between 1 January 2007 (the year these medications entered the UK market) and 31 December 2020

Pancreatic endocrine and exocrine signaling and crosstalk in physiological and pathological status

BMJ Case Rep 14(1):e235663

We appreciate the opportunity to testify on high drug costs

Recent studies have suggested the potential benefits of SGLT2 inhibitors, including empagliflozin, in slowing the progression of chronic kidney disease (CKD) in patients with type 2 diabetes, and reducing the risk of cardiovascular events.The decision to use empagliflozin in CKD should be made on a case-by-case basis, considering the patients overall kidney function and potential risks