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Gastrointestinal side effects such as nausea, vomiting, and diarrhea are the most commonly reported but typically improve over time
With retatrutide, the glucagon receptor is being activated pharmacologically on top of natural glucagon signaling
GPR120 (FFAR4) is preferentially expressed in pancreatic delta cells and regulates somatostatin secretion from murine islets of Langerhans
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