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Shifting your injection to a day that makes the peak tiredness window less disruptive - a Friday injection means the worst of it falls over the weekend, for example - is a simple practical adjustment that makes a real difference for some people

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Personal or Family History of Thyroid Cancer Semaglutide carries a boxed warning for patients with a personal or family history of medullary thyroid carcinoma (MTC), a rare but aggressive form of thyroid cancer

In addition, early data suggests possible renal protection

(David Paul Morris/Bloomberg / Getty Images) Glucagon-like peptide-1 (GLP-1) is a hormone that impacts glucose and is regulated by GLP-1 receptors