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Honest Comparison Semaglutide vs Tirzepatide: Honest Comparison At DermaVue, Mounjaro (tirzepatide) is our preferred first-line medication for most patients due to superior clinical outcomes

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Adding complementary peptides: Orforglipron addresses appetite and glycemic control but doesn't directly target body composition optimization, tissue repair, energy production, or other health dimensions

The body has adapted to the presence of the medication, and sudden removal disrupts multiple metabolic pathways simultaneously

Crucially for weight management, these medications act on appetite-regulating centres in the hypothalamus, reducing hunger signals and increasing satiety