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Furthermore, Trapp emphasises the significant barrier between the bloodstream and the brain the bloodbrain barrier (BBB)

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If your vial has been exposed to heat, direct sunlight, or prolonged room temperature storage, the compound may be less potent than expected, resulting in reduced effectiveness

The Reasoning: After a thorough review, the agency found no clinical need for these drugs to be compounded when FDA-approved versions are available and not in shortage