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1998;155:1626b1626

Left ventricular cardiac tissue was cut into small pieces approximately 2-3 mm thick, immediately fixed in electron microscopic solution (2.5% glutaraldehyde) for 24 hours, stained with toluidine blue for the more conspicuous areas, stained with 4% methanolic uranyl acetate and Reynolds lead citrate stain, and observed with a transmission electron microscope to observe the ultrastructure of mouse myocardial mitochondria (TM -3000
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Improvements were observed in some cardiovascular risk factors from baseline to week 120 (Figures 2 and S3 and Table 2), including for LDL cholesterol and CRP in both semaglutide and placebo arms and for HDL cholesterol, VLDL cholesterol and triglycerides in the semaglutide arm