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This mechanism drives weight loss but can trigger mild-to-moderate nausea, especially at higher doses or during dose escalation

The aim of this review is to synthesize the characteristics and the results of the most advanced clinical trials for the treatment of NASH to evaluate the recent advances of pharmacotherapy in this disease

Preclinical and observational evidence, as well as some small studies, suggested potential benefits of GLP-1 agonists, but this large trial does not confirm clinical efficacy in early Alzheimers. Have the authors taken confounding factors into account

High-Fat Foods Foods high in fat may slow digestion and increase the risk of nausea and vomiting [6]