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The most frequently reported symptoms include: Nausea (especially during dose increases) Vomiting Diarrhea Constipation Abdominal discomfort Decreased appetite (an expected effect of the medication) For most patients, side effects stay in the tolerable range and tend to taper off as treatment continues

If youre curious, read more about GLP-1 side effects and how to manage them here

Heres what tends to help and what to avoid

Seek urgent care for vomiting blood, black stools, or severe chest pain

Certain lifestyle changes can help people get the most benefit from GLP-1 medications and reduce side effects: Adequate protein intake: Eating enough protein (such as fish, poultry, yogurt, beans, or tofu) at each meal helps maintain muscle while losing weight