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Proprotein convertase (PC) is an important enzyme that activates the product of the pro-glucagon gene by cleaving a peptide at the C-terminal domain, thereby enabling the biological activity of this peptide

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Since patients with psoriatic arthritis already carry an elevated cardiovascular risk, this isnt only about joint pain it may also be about protecting the heart

Effect [edit] The incretin effect describes the phenomenon whereby oral glucose intake elicits a higher insulin response compared to intravenously introduced glucose that produces the same levels of serum glucose levels