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Plasma MOTS-c levels are associated with insulin sensitivity in lean but not in obese individuals

The absence of observed events should not be interpreted as evidence of safety for administering anesthesia with an unprotected airway in a population in which a substantial proportion of patients may present with a full stomach

A pragmatic way forward is to (i) use Bayesian inference to express uncertainty in clinically interpretable probabilities, and (ii) use data-driven phenotyping (including ML-enabled clustering where appropriate) to describe heterogeneity in treatment response

Both pre- and post-meal injectors in clinical trials achieved comparable weight loss when matched for dose and adherence over 1668 weeks