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Further, direct stimulation of the GLP-1 receptor on cholangiocytes can lead to enhanced cellular proliferation and an elevated likelihood of cholestasis [47]
See the information leaflet produced by the NHS below with advice about the current GLP-1 situation or download it here
The new trial thus strongly reinforces the benefit of GLP-1 for heart failure with preserved ejection fraction and extends that to people with Type 2 diabetes
The safety profile of orforglipron in Phase 3 trials has been consistent with the GLP-1 receptor agonist class
Understanding these costs is essential for patients considering this treatment option
