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GLP-1 receptor agonists affect sexual function differently across individuals and influencing libido and hormone levels in men and women during treatment.

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From the approval of Orlistat (Xenical) in 1999, which focused on reducing dietary fat absorption, to the emergence of highly effective incretin-based therapies such as liraglutide (Saxenda), semaglutide (Wegovy), and tirzepatide (Zepbound), we have witnessed a fundamental shift in how obesity is understood and treated

Summary-data-based MR (SMR) and IVW were used to calculate the effect estimates

This includes better sleep, improved mood, and increased energy levels