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[7] Both metformin and GLP-1RAs are known to improve leptin sensitivity, making the brain more responsive to the anorexigenic effects of the adipokine

Reducing food cravings and food noise

Semaglutide is a breakthrough medication belonging to a class of drugs known as GLP-1 (Glucagon-Like Peptide-1) receptor agonists

Theres also the issue most people are never told about: A significant part of the weight lost can be lean mass

Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas)
