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Microneedle-based drug delivery systems: microfabrication, drug delivery, and safety

In contrast, fasting GLP-1 concentrations negatively predict intake of food rich in simple sugars in a vending machine paradigm [113], which the authors interpreted as evidence that GLP-1 plays a role in reward pathways regulating simple sugar intake

While an imbalance of increased energy intake and reduced physical activity is considered the primary cause of obesity, research in this field has also highlighted genetics, disease, and environmental factors as significant contributors to its development [2,3,4]

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